Genes & Cancer

Volume 9: Issue 5-6, May 2018

pp153-256

Issue 5-6, May 2018

About the Cover

The cover for the issue of Genes & Cancer features Figure 3A (“Common ELF1 deletion in prostate cancer bolsters oncogenic ETS function, inhibits senescence and promotes docetaxel resistance”) from Budka et al.

Editorials

How a disruption of the competition between HIF-1 and p53 for limiting p300/CBP by latent viruses can cause disease

https://doi.org/10.18632/genesandcancer.178

Hanan Polansky, and Hava Schwab

p 153-154

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Reviews

Tumor metabolism regulating chemosensitivity in ovarian cancer

https://doi.org/10.18632/genesandcancer.176

Chae Young Han, David A. Patten, Richard B. Richardson, Mary-Ellen Harper, and Benjamin K. Tsang

p 155-175

Abstract |  PDF |  Full Text

The promising immune checkpoint LAG-3: from tumor microenvironment to cancer immunotherapy

https://doi.org/10.18632/genesandcancer.180

Long Long, Xue Zhang, Fuchun Chen, Qi Pan, Pronnaphat Phiphatwatchara, Yuyang Zeng, and Honglei Chen

p 176-189

Abstract |  PDF |  Full Text

Research Papers

Neoadjuvant administration of hydroxychloroquine in a phase 1 clinical trial induced plasma Par-4 levels and apoptosis in diverse tumors

https://doi.org/10.18632/genesandcancer.181

Peng Wang, Ravshan Burikhanov, Rani Jayswal, Heidi L. Weiss, Susanne M. Arnold, John L. Villano, and Vivek M. Rangnekar

p 190-197

Abstract |  PDF |  Full Text

Common ELF1 deletion in prostate cancer bolsters oncogenic ETS function, inhibits senescence and promotes docetaxel resistance

https://doi.org/10.18632/genesandcancer.182

Justin A. Budka, Mary W. Ferris, Matthew J. Capone, and Peter C. Hollenhorst

p 198-214

Abstract |  PDF |  Full Text |  Supplementary Materials

Pancreatic carcinoma cells colonizing the liver modulate the expression of their extracellular matrix genes

https://doi.org/10.18632/genesandcancer.179

Khamael M.K. Al-Taee, Michael Zepp, Irina Berger, Martin R. Berger, and Hassan Adwan

p 215-231

Abstract |  PDF |  Full Text

MicroRNA-messenger RNA interactions involving JAK-STAT signaling genes in colorectal cancer

https://doi.org/10.18632/genesandcancer.177

Lila E. Mullany, Jennifer S. Herrick, Lori C. Sakoda, Wade Samowitz, John R. Stevens, Roger K. Wolff, and Martha L. Slattery

p 232-246

Abstract |  PDF |  Full Text

Whole-transcriptome sequencing identified gene expression signatures associated with aggressive clear cell renal cell carcinoma

https://doi.org/10.18632/genesandcancer.183

Ken Batai, Elliot Imler, Jayce Pangilinan, Robert Bell, Aye Lwin, Elinora Price, Tijana Milinic, Amit Arora, Nathan A. Ellis, Erika Bracamonte, Bruce Seligmann, and Benjamin R. Lee

p 247-256

Abstract |  PDF |  Full Text |  Supplementary Materials