“In summary, our goal was to identify additional therapeutic targets for KRAS-driven PDAC.”

BUFFALO, NY- March 24, 2023 – A new research paper was published in Genes & Cancer on March 10, 2023, entitled, “VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer.”

Researchers have recently shown that proteins involved in the DNA damage response (DDR) are critical for KRAS-mutant pancreatic ductal

PRESS RELEASE: A new review was published in Genes & Cancer on February 1, 2023, entitled, “CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens.”

BUFFALO, NY- February 10, 2023 – A new review was published in Genes & Cancer on February 1, 2023, entitled, “CEACAMS 1, 5, and 6 in disease and cancer: interactions with pathogens.”

“Carcinoembryonic antigen (CEA), one of few FDA-approved biomarkers for cancer, was first

PRESS RELEASE: On January 30, 2023, a new research perspective was published in Genes & Cancer, entitled, “Leveraging a powerful allogeneic dendritic cell line towards neoantigen-based cancer vaccines.”

BUFFALO, NY- February 3, 2023 – A new research perspective was published in Genes & Cancer on January 30, 2023, entitled, “Leveraging a powerful allogeneic dendritic cell line towards neoantigen-based cancer vaccines.”

In recent

“Using secretome proteomics, we found that EWS::FLI1 induces the expression of Slit2. We demonstrate that EWS::FLI1 binds to the gene promoter of Slit2 and activates its expression.”

BUFFALO, NY- January 13, 2023 – A new research paper was published in Genes & Cancer on December 14, 2022, entitled, “Slit2 signaling stimulates Ewing sarcoma growth.”

Ewing sarcoma is a cancer of bone and soft tissue in children driven by EWS::ETS fusion,

On December 13, 2022, Genes & Cancer published a new review, entitled, “Pathogenesis to management of hepatocellular carcinoma.”

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BUFFALO, NY- January 6, 2023 – A new review was published in Genes & Cancer on December 13, 2022, entitled, “Pathogenesis to management of hepatocellular carcinoma.”

In this review, researchers Ben L. Da, Kelly I. Suchman, Lawrence Lau, Atoosa Rabiee, Aiwu Ruth He, Kirti Shetty, Herbert Yu, Linda L.