Genes & Cancer

Volume 5: Issue 11-12, November 2014

pp375-479

Issue 11-12, November 2014

About the Cover

The cover for Genes & Cancer features figure 7 (“RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells”) from Carper et al.

Meeting Reports

Origins of cancer symposium report: beyond the tumor cell

https://doi.org/10.18632/genesandcancer.35

Andrew M. Howard, Eric A. Nollet, and Nikki M. Thellman

p 375-377

Abstract |  PDF |  Full Text

Research Papers

STAT activation status differentiates leukemogenic from non-leukemogenic stem cells in AML and is suppressed by arsenic in t(6;9)-positive AML

https://doi.org/10.18632/genesandcancer.39

Claudia Oancea, Brigitte Rüster, Boris Brill, Jessica Roos, Maria Heinssmann, Gesine Bug, Afsar Ali Mian, Nathalie Andrea Guillen, Steven M. Kornblau, Reinhard Henschler, and Martin Ruthardt

p 378-392

Abstract |  PDF |  Full Text |  Supplementary Material

mTORC2 modulates feedback regulation of p38 MAPK activity via DUSP10/MKP5 to confer differential responses to PP242 in glioblastoma

https://doi.org/10.18632/genesandcancer.41

Angelica Benavides-Serrato, Lauren Anderson, Brent Holmes, Cheri Cloninger, Nicholas Artinian, Tariq Bashir, and Joseph Gera

p 393-406

Abstract |  PDF |  Full Text |  Supplementary Materials

DEPTOR is linked to a TORC1-p21 survival proliferation pathway in multiple myeloma cells

https://doi.org/10.18632/genesandcancer.44

Yonghui Yang, Carolyne Bardeleben, Patrick Frost, Bao Hoang, Yijiang Shi, Richard Finn, Joseph Gera, and Alan Lichtenstein

p 407-419

Abstract |  PDF |  Full Text |  Supplementary Materials

RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells

https://doi.org/10.18632/genesandcancer.43

Miranda B. Carper, James Denvir, Goran Boskovic, Donald A. Primerano, and Pier Paolo Claudio

p 420-435

Abstract |  PDF |  Full Text |  Supplementary Materials |  Supplementary Materials

Tumor suppression by miR-31 in esophageal carcinoma is p21-dependent

https://doi.org/10.18632/genesandcancer.38

Zhifeng Ning, Hua Zhu, Feifei Li, Qing Liu, Gefei Liu, Tao Tan, Bo Zhang, Shaobin Chen, Guanwu Li, Dongyang Huang, Stephen J Meltzer, and Hao Zhang

p 436-444

Abstract |  PDF |  Full Text |  Supplementary Materials

The Bcl-2 inhibitor Obatoclax overcomes resistance to histone deacetylase inhibitors SAHA and LBH589 as radiosensitizers in patient-derived glioblastoma stem-like cells

https://doi.org/10.18632/genesandcancer.42

Lotte M.E. Berghauser Pont, Jochem K.H. Spoor, Subramanian Venkatesan, Sigrid Swagemakers, Jenneke J. Kloezeman, Clemens M.F. Dirven, Peter J. van der Spek, Martine L.M. Lamfers, and Sieger Leenstra

p 445-459

Abstract |  PDF |  Full Text

Taurolidine cooperates with antineoplastic drugs in neuroblastoma cells

https://doi.org/10.18632/genesandcancer.36

Georg Eschenburg, Christian Luckert, Konrad Reinshagen, and Robert Bergholz

p 460-469

Abstract |  PDF |  Full Text

The antihypertension drug doxazosin suppresses JAK/STATs phosphorylation and enhances the effects of IFN-α/γ-induced apoptosis

https://doi.org/10.18632/genesandcancer.37

Mi Sun Park, Boh-Ram Kim, Sokbom Kang, Dae-Yong Kim, and Seung Bae Rho

p 470-479

Abstract |  PDF |  Full Text