Genes & Cancer

Volume 5: Issue 7-8, July 2014


Issue 7-8, July 2014

About the Cover

The cover for Genes & Cancer features figure 1C ("Functional antagonism of TMPRSS2-ERG splice variants in prostate cancer") from Rastogi et al.

Research Papers

PTEN deficiency and mutant p53 confer glucose-addiction to thyroid cancer cells: impact of glucose depletion on cell proliferation, cell survival, autophagy and cell migration

Federica Morani, Suratchanee Phadngam, Carlo Follo, Rossella Titone, Visa Thongrakard, Alessandra Galetto, Oscar Alabiso, and Ciro Isidoro

p 226-239

Abstract |  PDF |  Full Text

Impairement of HT29 cancer cells cohesion by the soluble form of neurotensin receptor-3

Fabienne Massa, Christelle Devader, Sandra Lacas-Gervais, Sophie BĂ©raud-Dufour, Thierry Coppola, and Jean Mazella

p 240-249

Abstract |  PDF |  Full Text

CD133-positive cancer stem cells from colo205 human colon adenocarcinoma cell line show resistance to chemotherapy and display a specific metabolomic profile

Zangiacomi Vincent, Kenichi Urakami, Koji Maruyama, Ken Yamaguchi, and Masatoshi Kusuhara

p 250-260

Abstract |  PDF |  Full Text |  Supplementary Materials

CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models

Agnieszka K. Witkiewicz, Derek Cox, and Erik S. Knudsen

p 261-272

Abstract |  PDF |  Full Text

Functional antagonism of TMPRSS2-ERG splice variants in prostate cancer

Anshu Rastogi, Shyh-Han Tan, Ahmed A. Mohamed, Yongmei Chen, Ying Hu, Gyorgy Petrovics, Taduru Sreenath, Jacob Kagan, Sudhir Srivastava, David G. McLeod, Isabell A. Sesterhenn, Shiv Srivastava, Albert Dobi, and Alagarsamy Srinivasan

p 273-284

Abstract |  PDF |  Full Text

Impact of DNA repair pathways on the cytotoxicity of piperlongumine in chicken DT40 cell-lines.

Saki Okamoto, Takeo Narita, Hiroyuki Sasanuma, Shunichi Takeda, Shin-ichiro Masunaga, Tadayoshi Bessho, and Keizo Tano

p 285-292

Abstract |  PDF |  Full Text |  Supplementary Materials

NVP-BEZ-235 enhances radiosensitization via blockade of the PI3K/mTOR pathway in cisplatin-resistant non-small cell lung carcinoma.

Kwang Woon Kim, Carey J. Myers, Dae Kwang Jung, and Bo Lu

p 293-302

Abstract |  PDF |  Full Text