Volume 6: Issue 3-4, March 2015
pp82-181
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About the CoverThe cover for Genes & Cancer features figure S6 (“EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma”) from Fadul et al. |
Editorials
Biguanides and targeted anti-cancer treatments
https://doi.org/10.18632/genesandcancer.59
Elyse K. Hanly, Zbigniew Darzynkiewicz, and Raj K. Tiwari
p 82-83
Reviews
Trop2 and its overexpression in cancers: regulation and clinical/ therapeutic implications
https://doi.org/10.18632/genesandcancer.40
Anna Shvartsur, and Benjamin Bonavida
p 84-105
Research Papers
Requirement for BUB1B/BUBR1 in tumor progression of lung adenocarcinoma
https://doi.org/10.18632/genesandcancer.53
Honglin Chen, James Lee, Noelyn M. Kljavin, Benjamin Haley, Anneleen Daemen, Leisa Johnson, and Yuxin Liang
p 106-118
Drug sensitivity profiling and molecular characteristics of cells from pleural effusions of patients with lung adenocarcinoma
https://doi.org/10.18632/genesandcancer.56
Rita Ötvös, Adam Szulkin, Carl-Olof Hiilerdal, Aytekin Celep, Eviane Yousef-Fadhel, Henriette Skribek, Anders Hjerpe, Laszlo Szekely, and Katalin Dobra
p 119-128
EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma
https://doi.org/10.18632/genesandcancer.57
John Fadul, Russell Bell, Laura M. Hoffman, Mary C. Beckerle, Michael E. Engel, and Stephen L. Lessnick
p 129-143
Triptolide and its prodrug minnelide suppress Hsp70 and inhibit in vivo growth in a xenograft model of mesothelioma
https://doi.org/10.18632/genesandcancer.55
Blake A. Jacobson, Esther Z. Chen, Shaogeng Tang, Holly Sedgwick Belgum, Joel A. McCauley, Kristen A. Evenson, Ryan G. Etchison, Joe Jay-Dixon, Manish R. Patel, Ahmad Raza, Ashok K. Saluja, Jonathan D’Cunha, and Robert A. Kratzke
p 144-152
Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer
https://doi.org/10.18632/genesandcancer.58
Jennifer E. Yeh, Simion Kreimer, Sarah R. Walker, Megan M. Emori, Hannah Krystal, Andrea Richardson, Alexander R. Ivanov, and David A. Frank
p 153-168
Suberoylanilide hydroxamic acid (SAHA) reverses chemoresistance in head and neck cancer cells by targeting cancer stem cells via the downregulation of nanog
https://doi.org/10.18632/genesandcancer.54
Bhavna Kumar, Arti Yadav, James C. Lang, Theodoros N. Teknos, and Pawan Kumar
p 169-181