Genes & Cancer

Volume 6: Issue 5-6, May 2015


Issue 5-6, May 2015

About the Cover

The cover for Genes & Cancer features figure 1 (“Screening of suppressors of bax-induced cell death identifies glycerophosphate oxidase-1 as a mediator of debcl-induced apoptosis in Drosophila”) from Colin et al.


Wee1 and Chk1 – crosstalk between key players in replicative stress

Priyanka Saini, Yizhu Li, and Matthias Dobbelstein

p 182-183



Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancy

Leila Haery, Ryan C. Thompson, and Thomas D. Gilmore

p 184-213

Abstract |  PDF |  Full Text

Research Perspective

Chronic inflammation: is it the driver or is it paving the road for malignant transformation?

Kambiz Afrasiabi, Yi-Hong Zhou, and Angela Fleischman

p 214-219

Abstract |  PDF |  Full Text

Research Papers

CArG-driven GADD45α activated by resveratrol inhibits lung cancer cells

Qiwen Shi, Werner Geldenhuys, Vijaykumar Sutariya, Anupam Bishayee, Isha Patel, and Deepak Bhatia

p 220-230

Abstract |  PDF |  Full Text

RASSF10 suppresses hepatocellular carcinoma growth by activating P53 signaling and methylation of RASSF10 is a docetaxel resistant marker

Yongshuai Jin, Baoping Cao, Meiying Zhang, Qimin Zhan, James G. Herman, Miao Yu, and Mingzhou Guo

p 231-240

Abstract |  PDF |  Full Text

Screening of suppressors of bax-induced cell death identifies glycerophosphate oxidase-1 as a mediator of debcl-induced apoptosis in Drosophila

Jessie Colin, Julie Garibal, Amandine Clavier, Sébastien Szuplewski, Yanick Risler, Cécile Milet, Sébastien Gaumer, Isabelle Guénal, and Bernard Mignotte

p 241-253

Abstract |  PDF |  Full Text

PSCA s2294008 C>T and rs2976392 G>A polymorphisms contribute to cancer susceptibility: evidence from published studies

Yong Gu, Qiang-Sheng Dai, Rui-Xi Hua, Bing Zhang, Jin-Hong Zhu, Jian-Wen Huang, Bin-Hui Xie, Shi-Qiu Xiong, Guo-Sheng Tan, and He-Ping Li

p 254-264

Abstract |  PDF |  Full Text

3,3’-Diindolylmethane (DIM) and its ring-substituted halogenated analogs (ring-DIMs) induce differential mechanisms of survival and death in androgen-dependent and –independent prostate cancer cells

Alexander A. Goldberg, Hossam Draz, Diana Montes-Grajales, Jesus Olivero-Verbél, Stephen H. Safe, and J. Thomas Sanderson

p 265-280

Abstract |  PDF |  Full Text |  Supplementary Materials

Circulating microRNAs - a new horizon in molecular diagnosis of breast cancer

Hoda A. Hagrass, Samar Sharaf, Heba F. Pasha, Enas A. Tantawy, Randa H. Mohamed, and Rasha Kassem

p 281-287

Abstract |  PDF |  Full Text